What are ICC (inherited cardiac conditions)?

Inherited cardiac conditions (ICC) are genetic disorders that affect the function of the heart. About 1% of people worldwide have ICC.

Main Types of Inherited Cardiac Conditions (ICC):
  • Hypertrophic Cardiomyopathy
  • Dilated Cardiomyopathy
  • Arrhythmogenic Right Ventricle Cardiomyopathy
  • Left Ventricular Non-Compaction
  • Inherited Amyloidosis
  • Fabry Disease
  • Danon Disease
  • Marfan Syndrome
  • Loeys-Dietz
  • Brugada Syndrome
  • Long QT Syndrome
  • Short QT Syndrome
  • Catecholaminergic Polymorphic Ventricular Tachycardia
  • Familial Hypercholesterolemia / Dyslipidemia
  • Familial Hypertriglyceridemia
  • Inherited Pulmonary Artery Hypertension genes

Why is genetic testing for
ICC important?

Identifying the genetic cause of your condition is important for several reasons.

  • Genetic testing may benefit you and your family by confirming your diagnosis of an inherited cardiac condition (ICC).
  • Genetic testing results can assist clinician to make decisions to best manage your cardiac condition.
  • Genetic testing can also help to identify family members who are at risk of ICC, so they can seek preventive care before developing symptoms.

Who should consider using CardioICC?

Genetic testing should be done for anyone with a suspected genetic cause for his or her condition.

The chance of finding a genetic cause is higher when you have a family member who may have cardiac conditions. However, even without a family disease history, it is also possible to have a genetic mutation that causes cardiac conditions.

If we find a genetic mutation in a patient, CardioICC is strongly advised for other family members as well, regardless of presence of ICC symptoms. This helps them to determine their ICC risk, which can be useful in planning medical action.

What are
symptoms of ICC?

  • Chest pain
  • Cough
  • Fainting (syncope)
  • Shortness of breath (dyspnea)
  • Fatigue
  • Palpitations/ rapid heartbeat (arrhythmia)
  • Swelling of ankles and feet

How does CardioICC work?

CardioICC is a genetic test for inherited cardiac conditions (ICC).

NOTE : We do not release the report to family members without your permission.


A small sample of blood will be taken from you.


CardioICC will extract DNA from your blood sample, and search for genetic mutations associated with cardiac conditions.


A personalized report will be generated.


Your doctor will explain the report to you, and will provide you further recommendations.

What can cause ICC?

ICC are caused by mutations (changes) in our genes. A person may develop ICC in two ways:


If one of the parents has ICC.
The child has a 50% chance of inheriting ICC.


Patient may be the first in the family to carry a ICC mutation.
The mutation can pass on to his/her child.

How can I request
for a test?

  • A 3ml EDTA blood sample
  • Buccal swab is an alternative